Ammonium Hydroxide → beta-Phenyl-L-phenylalanine

HRID 1614697

반응식

HRID 1614697 반응식
Cl.[C:2]1([CH:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C@@H:9]([C:11]([OH:13])=[O:12])[NH2:10])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[NH4+]>O>[C:2]1([CH:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C@@H:9]([C:11]([OH:13])=[O:12])[NH2:10])[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 14923Ammonium HydroxideHCID 70136519(S)-2-Amino-3,3-diphenylpropanoic acid hydrochloride

생성물 1

HCID 162977beta-Phenyl-L-phenylalanine수율 46%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

D (-)-3,3-Diphenylalanine hydrochloride (0.5 g) is dissolved in 15 mL of water and the pH of the solution is adjusted with dilute ammonium hydroxide solution to pH 7. The precipitate is collected by filtration, washed with water, boiled with water for a short time, cooled to room temperature, and collected to afford 0.2 g of the title compound; mp 218°-220° C. (dec.).

후처리

  1. filtrationThe precipitate is collected by filtration
  2. washwashed with water
  3. customcollected

출처 및 근거

ORD 기록
ord-138ffbe38f4746daa81b966f03e18082
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05198548

연결된 노트

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