Borane → HCID 68758903, 화합물

HRID 1615263노트

반응식

HRID 1615263 반응식
[Br:1][C:2]1[CH:10]=[C:9]([C:11](O)=[O:12])[CH:8]=[C:7]2[C:3]=1[CH:4]=[N:5][NH:6]2.B>>[Br:1][C:2]1[CH:10]=[C:9]([CH2:11][OH:12])[CH:8]=[C:7]2[C:3]=1[CH:4]=[N:5][NH:6]2

참가 물질

3

반응물 2

HCID 6331BoraneHCID 247284024-Bromo-1H-indazole-6-carboxylic acid

생성물 1

HCID 68758903HCID 68758903, 화합물수율 88.1%

실험 절차

According to the method of A52A, 4-bromo-1H-indazole-6-carboxylic acid (1 g, 4 mmol) was reacted with borane (6 ml, 6 mmol) to give the title compound as a pale yellow solid (800 mg, 88%). MS ESI [M+H]+, calcd for [C8H7BrN2O+H]+ 227.0, 229.0; found m/z 226.9, 228.9.

출처 및 근거

ORD 기록
ord-b8e0bffa1cd745469a7fa3e015c4ab7f
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08765748B2

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