Oxindole → HCID 178517042, 화합물

HRID 1615265노트

반응식

HRID 1615265 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10].[Br:11][C:12]1[CH:20]=[C:19]([CH:21]=O)[CH:18]=[C:17]2[C:13]=1[CH:14]=[N:15][NH:16]2>>[Br:11][C:12]1[CH:20]=[C:19]([CH:21]=[C:3]2[C:4]3[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=3)[NH:1][C:2]2=[O:10])[CH:18]=[C:17]2[C:13]=1[CH:14]=[N:15][NH:16]2

참가 물질

3

반응물 2

HCID 321710OxindoleHCID 596355854-bromo-1H-indazole-6-carbaldehyde

생성물 1

HCID 178517042HCID 178517042, 화합물

실험 절차

According to the method described for Example A1, oxindole (15 mg, 0.11 mmol) was reacted with 4-bromo-1H-indazole-6-carbaldehyde (25 mg, 0.11 mmol) to give the title compound as an orange solid. The E and Z stereoisomers were separated by HPLC.

출처 및 근거

ORD 기록
ord-df681744216143b8a2c77bc011f74e53
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08765748B2

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