Dimethylformamide → 5-Bromo-1-methyl-3-[5-(4-methyl-piperazine-1-carbonyl)-pyridin-2-ylamino]-1H-pyridin-2-one

반응식

[CH3:27][N:28]([CH3:29])[CH:30]=[O:31].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH3:16])[CH2:14][CH2:15]2)[cH:6][n:7]1.[NH2:17][c:18]1[c:19](=[O:26])[n:20]([CH3:25])[cH:21][c:22]([Br:24])[cH:23]1>>[c:2]1([NH:17][c:18]2[c:19](=[O:26])[n:20]([CH3:25])[cH:21][c:22]([Br:24])[cH:23]2)[cH:3][cH:4][c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH3:16])[CH2:14][CH2:15]2)[cH:6][n:7]1

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 9020401-(6-Chloropyridine-3-carbonyl)-4-methylpiperazine

HCID 529112683-Amino-5-bromo-1-methyl-1,2-dihydropyridin-2-one

생성물 1

HCID 592164415-Bromo-1-methyl-3-[5-(4-methyl-piperazine-1-carbonyl)-pyridin-2-ylamino]-1H-pyridin-2-one

출처 및 근거

ORD 기록: ord-ec57cbe881cd45c08c50e8c849ef9e37
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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