Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Dimethylamino)butan-1-ol → 4-(Dimethylamino)butyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Dimethylamino)butan-1-ol | HCID 83350 | — |
| 반응물 | 2-(4-((2-Amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetic acid | HCID 68414136 | — |
| 생성물 | 4-(Dimethylamino)butyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetate | HCID 57824844 | — |
반응 단계
The title compound was prepared using product of example 79 step (i) (80 mg) and 4-(dimethylamino)butan-1-ol using the general coupling method of example 74 step (iii). The product was purified by RPHPLC to give the product, 25 mg.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08765939B2 |
| 출처 데이터셋 | uspto-grants-2014_07 |
| ORD ID | ord-8cfc86100e3348eb866ce21acd8e6255 |
| 출처 메모 | uspto-grants-2014_07 |