Thionyl Chloride → 2-(1-(2-Methoxyethyl)piperidin-4-ylidene)acetyl chloride hydrochloride

HRID 1617279노트

반응식

[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][C:8](=[CH:11][C:12]([OH:14])=O)[CH2:7][CH2:6]1.S(Cl)([Cl:17])=O>>[ClH:17].[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][C:8](=[CH:11][C:12]([Cl:17])=[O:14])[CH2:7][CH2:6]1

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 593826602-(1-(2-Methoxyethyl)piperidin-4-ylidene)acetic acid

생성물 1

HCID 866297582-(1-(2-Methoxyethyl)piperidin-4-ylidene)acetyl chloride hydrochloride

실험 절차

2.4 g of 2-(1-(2-methoxyethyl)piperidin-4-ylidene)acetic acid was dissolved in 20 mL of thionyl chloride, refluxed for 2 hours, evaporated in vacuo to remove thionyl chloride and give a solid product.

후처리

temperaturerefluxed for 2 hours
customevaporated in vacuo
customto remove thionyl chloride
customgive a solid product

출처 및 근거

ORD 기록: ord-c1b268ae301e417990aa25469425606d
출처 데이터셋: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08765946B2

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