4-Bromo-2-methylpyridine → 1-(2-Methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one

반응식

CON(C)[C:4](=[O:19])[CH2:5][CH:6]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.Br[C:22]1[CH:27]=[CH:26][N:25]=[C:24]([CH3:28])[CH:23]=1>>[CH3:28][C:24]1[CH:23]=[C:22]([C:4](=[O:19])[CH2:5][CH:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:27]=[CH:26][N:25]=1

참가 물질

반응물 2

HCID 27628354-Bromo-2-methylpyridine

HCID 54293842N-Methoxy-N-methyl-3,3-diphenyl-propionamide

생성물 1

HCID 670155831-(2-Methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one

실험 절차

In analogy to example 55, step 2, the title compounds was prepared from N-methoxy-N-methyl-3,3-diphenyl-propionamide and 4-bromo-2-methylpyridine as a colorless oil, MS (ESI+): m/z=302.15 ([M+H]+).

출처 및 근거

ORD 기록: ord-ef5083a14cbb4643896fdc0188aec3a7
출처 데이터셋: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08765730B2

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