Sodium t-butoxide → 1'-(5,7-Difluoro-3-methyl-2-(2-(methylsulfonyl)phenyl)-4-quinolinyl)-6'-(4-morpholinyl)-1',2,2',3,5,6-hexahydrospiro-[pyran-4,3'-pyrrolo[3,2-b]pyridine]

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Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([F:13])=[CH:9][C:10]=2[F:12])[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[S:20]([CH3:23])(=[O:22])=[O:21])[C:3]=1[CH3:24].[O:25]1[CH2:30][CH2:29][N:28]([C:31]2[CH:32]=[C:33]3[NH:39][CH2:38][C:37]4([CH2:44][CH2:43][O:42][CH2:41][CH2:40]4)[C:34]3=[N:35][CH:36]=2)[CH2:27][CH2:26]1.CC(C)([O-])C.[Na+]>CC(C1C=C(C(C)C)C(C2C(P(C3CCCCC3)C3CCCCC3)=CC=CC=2)=C(C(C)C)C=1)C.C1C=[C-]C(CCN)=CC=1.Cl[Pd+].C1(C)C=CC=CC=1>[F:12][C:10]1[CH:9]=[C:8]([F:13])[CH:7]=[C:6]2[C:11]=1[C:2]([N:39]1[C:33]3[C:34](=[N:35][CH:36]=[C:31]([N:28]4[CH2:29][CH2:30][O:25][CH2:26][CH2:27]4)[CH:32]=3)[C:37]3([CH2:44][CH2:43][O:42][CH2:41][CH2:40]3)[CH2:38]1)=[C:3]([CH3:24])[C:4]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[S:20]([CH3:23])(=[O:22])=[O:21])=[N:5]2