Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxalyl chloride → N-[(1-Butyl-4-piperidinyl)methyl]5-chloro-2-methylbenzoxazole-7-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 4-Aminomethyl-1-N-butylpiperidine | HCID 10442133 | — |
| 반응물 | 5-Chloro-2-methylbenzoxazole-7-carboxylic acid | HCID 19691864 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | N-[(1-Butyl-4-piperidinyl)methyl]5-chloro-2-methylbenzoxazole-7-carboxamide | HCID 19691850 | — |
반응 단계
5-Chloro-2-methylbenzoxazole-7-carboxylic acid (Ger. Offen. 2,225,544) is converted to its acid chloride by treatment with oxalyl chloride. The acid chloride is treated with N-(1-butyl-4-piperidinyl)methylamine in the presence of triethylamine to afford the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05726187 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-6d542e3dbdd248a898a4ea74dbd0c2eb |
| 출처 메모 | uspto-grants-1998_03 |