Dimethylformamide → Telmisartan

HRID 161922노트

반응식

[CH2:1]([CH2:2][CH3:3])[c:4]1[n:5][c:6]2[c:7]([n:8]1[CH2:9][c:10]1[cH:11][cH:12][c:13](-[c:16]3[c:17]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[cH:18][cH:19][cH:20][cH:21]3)[cH:14][cH:15]1)[cH:29][c:30](-[c:34]1[n:35][c:36]3[c:37]([n:38]1[CH3:39])[cH:40][cH:41][cH:42][cH:43]3)[cH:31][c:32]2[CH3:33].[CH3:51][N:52]([CH3:53])[CH:54]=[O:55].[OH:44][C:45]([C:46]([F:47])([F:48])[F:49])=[O:50]>>[CH2:1]([CH2:2][CH3:3])[c:4]1[n:5][c:6]2[c:7]([n:8]1[CH2:9][c:10]1[cH:11][cH:12][c:13](-[c:16]3[c:17]([C:22](=[O:23])[OH:24])[cH:18][cH:19][cH:20][cH:21]3)[cH:14][cH:15]1)[cH:29][c:30](-[c:34]1[n:35][c:36]3[c:37]([n:38]1[CH3:39])[cH:40][cH:41][cH:42][cH:43]3)[cH:31][c:32]2[CH3:33]

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 6422Trifluoroacetic acid

HCID 10076748Telmisartan tert-butyl ester

생성물 1

HCID 65999Telmisartan

출처 및 근거

ORD 기록: ord-bcaee79e6357468f85aa94f41a04906b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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