(2-Thiophen-2-yl-benzoxazol-6-yl)methanol → 2-Thiophen-2-yl-benzoxazole-6-carbaldehyde

HRID 1619998노트

반응식

HRID 1619998 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][C:8]2[CH:14]=[C:13]([CH2:15][OH:16])[CH:12]=[CH:11][C:9]=2[N:10]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:7][C:8]2[CH:14]=[C:13]([CH:15]=[O:16])[CH:12]=[CH:11][C:9]=2[N:10]=1

참가 물질

4

반응물 1

HCID 67466243(2-Thiophen-2-yl-benzoxazol-6-yl)methanol

생성물 1

HCID 820366102-Thiophen-2-yl-benzoxazole-6-carbaldehyde

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 6344Dichloromethane용매

실험 절차

3.7 g (16.0 mmol) (2-thiophen-2-yl-benzoxazol-6-yl)-methanol are dissolved in 200 ml DCM, 15.0 g (10.78 mmol) manganese dioxide are added and the suspension is stirred overnight at RT. The next day the suspension is filtered through kieselguhr and the filtrate is concentrated completely by rotary evaporation i. V.

후처리

  1. filtrationThe next day the suspension is filtered through kieselguhr
  2. concentrationthe filtrate is concentrated completely by rotary evaporation i

출처 및 근거

ORD 기록
ord-6b136be23d0844fe8f7d4c78d963c661
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08772323B2

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