Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydrofuran → 7-Hydroxychromanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 3-Hydroxycoumarin | HCID 13650 | — |
| 촉매 | Palladium hydroxide | HCID 9942167 | — |
| 생성물 | 7-Hydroxychromanone | HCID 298130 | — |
반응 단계
A solution of hydroxycoumarin (2.0 g, TCI) in anhydrous THF (50 ml) was added with 10% palladium hydroxide/activated carbon (1.0 g, WAKO), and stirred at room temperature for 2 hours under hydrogen atmosphere. The atmosphere was replaced with nitrogen gas, and then the insoluble matters were removed by filtration through Celite. The solvent was evaporated under reduced pressure to obtain the title compound (2.0 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08772327B2 |
| 출처 데이터셋 | uspto-grants-2014_07 |
| ORD ID | ord-42b5a6e743ec43ad98e4c4167e7422da |
| 출처 메모 | uspto-grants-2014_07 |