4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178518110, 화합물
반응식
[NH2:1][CH2:2][C:3]1([CH2:7][OH:8])[CH2:6][CH2:5][CH2:4]1.S=[C:10]1[CH2:14][S:13][C:12](=[O:15])[NH:11]1>C(O)C>[OH:8][CH2:7][C:3]1([CH2:2][NH:1][C:10]2[CH2:14][S:13][C:12](=[O:15])[N:11]=2)[CH2:6][CH2:5][CH2:4]1참가 물질
4
실험 절차
To a solution of [1-(aminomethyl)cyclobutyl]methanol (1.00 g) in ethanol (30 mL) was added 4-thioxo-1,3-thiazolidin-2-one (1.16 g), and the mixture was heated under reflux overnight. The reaction mixture was concentrated under reduced pressure, and the obtained powder was washed with ethyl acetate to give the title compound (795 mg).
후처리
- temperaturethe mixture was heated
- temperatureunder reflux overnight
- concentrationThe reaction mixture was concentrated under reduced pressure
- washthe obtained powder was washed with ethyl acetate
출처 및 근거
- ORD 기록
- ord-09509325a6e44c5f96c0792b469854ab
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08772277B2
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