4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178484550, 화합물
반응식
S=[C:2]1[CH2:6][S:5][C:4](=[O:7])[NH:3]1.Cl.[CH3:9][N:10]([CH3:16])[C:11](=[O:15])[CH2:12][CH2:13][NH2:14]>C(O)C>[CH3:9][N:10]([CH3:16])[C:11](=[O:15])[CH2:12][CH2:13][NH:14][C:2]1[CH2:6][S:5][C:4](=[O:7])[N:3]=1참가 물질
4
실험 절차
To a solution of N,N-dimethyl-R-alaninamide (2.12 g) in ethanol (25 mL) was added 4-thioxo-1,3-thiazolidin-2-one (2.43 g), which N,N-dimethyl-β-alaninamide hydrochloride was treated with AMBERLYST (registered trademark) A21, and the mixture was stirred at room temperature overnight. The reaction mixture was concentrated, and the residue was purified by silica gel column chromatography (NH, ethyl acetate/methanol) to give the title compound (0.33 g).
후처리
- additionwas treated with AMBERLYST (registered trademark) A21
- concentrationThe reaction mixture was concentrated
- customthe residue was purified by silica gel column chromatography (NH, ethyl acetate/methanol)
출처 및 근거
- ORD 기록
- ord-da1ffbcf55f84ad19c2903de37d7f420
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08772277B2
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