4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178484598, 화합물
반응식
[OH:1][C:2]([CH3:11])([CH3:10])[C@@H:3]([C:5]([N:7]([CH3:9])[CH3:8])=[O:6])[NH2:4].S=[C:13]1[CH2:17][S:16][C:15](=[O:18])[NH:14]1>C(O)C>[OH:1][C:2]([CH3:11])([CH3:10])[C@@H:3]([C:5]([N:7]([CH3:9])[CH3:8])=[O:6])[NH:4][C:13]1[CH2:17][S:16][C:15](=[O:18])[N:14]=1참가 물질
4
실험 절차
To a solution of the crude product containing 3-hydroxy-N,N-dimethyl-L-valinamide obtained in C) in ethanol (5 mL) was added 4-thioxothiazolidin-2-one (380 mg) at room temperature. The reaction mixture was stirred at room temperature overnight, The solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane) to give the title compound (300 mg).
후처리
- customThe solvent was evaporated under reduced pressure
- customThe residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane)
출처 및 근거
- ORD 기록
- ord-2d9e22e491c649bbb66ce1a85e39604d
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08772277B2
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