Potassium hydroxy sulfite → 2-(5-(Methylsulfinyl)thiazol-2-ylcarbamoyl)phenyl acetate

HRID 1620891

반응식

HRID 1620891 반응식
[OH:1]OS([O-])=O.[K+].C(OC1C=CC=CC=1C(=O)NC1SC=C(S(C)=O)N=1)(=O)C.[C:28]([O:31][C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][C:33]=1[C:38](=[O:47])[NH:39][C:40]1[S:41][C:42]([S:45][CH3:46])=[CH:43][N:44]=1)(=[O:30])[CH3:29]>>[C:28]([O:31][C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][C:33]=1[C:38](=[O:47])[NH:39][C:40]1[S:41][C:42]([S:45]([CH3:46])=[O:1])=[CH:43][N:44]=1)(=[O:30])[CH3:29]

참가 물질

4

반응물 3

HCID 23707502Potassium hydroxy sulfiteHCID 497757802-(5-(Methylthio)thiazol-2-ylcarbamoyl)phenyl acetateHCID 569691682-{[4-(Methylsulfinyl)-1,3-thiazol-2-yl]carbamoyl}phenyl acetate

생성물 1

HCID 569693972-(5-(Methylsulfinyl)thiazol-2-ylcarbamoyl)phenyl acetate

실험 절차

Using the Oxone® procedure as described in section 1.5.1.7 for the synthesis of compound (1), 518 (1.1 g, 3.57 mmol), affords 11 as a white solid.

출처 및 근거

ORD 기록
ord-b28020a277954207922ec073dfaec2d5
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08772502B2

연결된 노트

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