3,4-Diaminobenzimidamide hydrochloride → HCID 178479303, 화합물
반응식
C[O:2][C:3]([C:5]1[CH:6]=[C:7]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([S:26](=[O:33])(=[O:32])[NH:27]C(C)(C)C)[CH:21]=2)[C:8]([O:13]COCCOC)=[C:9]([CH:11]=O)[CH:10]=1)=[O:4].[ClH:34].[NH2:35][C:36]1[CH:37]=[C:38]([CH:42]=[CH:43][C:44]=1[NH2:45])[C:39]([NH2:41])=[NH:40]>>[ClH:34].[C:39]([C:38]1[CH:42]=[CH:43][C:44]2[NH:45][C:11]([C:9]3[CH:10]=[C:5]([C:3]([OH:2])=[O:4])[CH:6]=[C:7]([C:20]4[CH:25]=[CH:24][CH:23]=[C:22]([S:26](=[O:32])(=[O:33])[NH2:27])[CH:21]=4)[C:8]=3[OH:13])=[N:35][C:36]=2[CH:37]=1)(=[NH:40])[NH2:41]참가 물질
3
실험 절차
Proceeding as in Reference 23, but substituting 3′-tert-butylsulfamoyl-5-formyl-6-(2-methoxyethoxymethoxy)-biphenyl-3-carboxylic acid methyl ester (1.64 g, 3.42 mmol, 1.0 eq.) and 3,4-diamino-benzamidine hydrochloride (638 mg, 3.42 mmol, 1.0 eq.), gave 5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6-hydroxy-3′-sulfamoyl-biphenyl-3-carboxylic acid hydrochloride (650 mg) as a brown solid.
출처 및 근거
- ORD 기록
- ord-55d6ef90e60e4467a5368d22fb47ee15
- 출처 데이터셋