1,3,4-Oxadiazole, 2-amino-5-phenyl- → [5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-ylmethyl]-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]=O)=[CH:4][CH:3]=1.[C:16]1([C:22]2[O:26][C:25]([NH2:27])=[N:24][N:23]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH2:14][NH:27][C:25]2[O:26][C:22]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[N:23][N:24]=2)=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 153631,3,4-Oxadiazole, 2-amino-5-phenyl-

HCID 821337925-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde

생성물 1

HCID 66579240[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-ylmethyl]-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine

실험 절차

Prepared according to the procedure described in Example 2, using 5-(4-bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde and 5-phenyl-[1,3,4]oxadiazol-2-ylamine.

후처리

customPrepared

출처 및 근거

ORD 기록: ord-c867f9d598e942dd9edc5c7ac1ba52d6
출처 데이터셋: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08778983B2

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