Dimethylformamide → 1-[4-[4-Amino-7-[3-[2-(methoxymethyl)pyrrolidin-1-yl]propyl]pyrrolo[2,1-f][1,2,4]triazin-5-yl]-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea

HRID 162457

반응식

[CH3:37][O:38][CH2:39][CH:40]1[NH:41][CH2:42][CH2:43][CH2:44]1.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:15]1[cH:16][c:17]([F:36])[c:18]([NH:21][C:22](=[O:23])[NH:24][c:25]3[c:26]([F:35])[cH:27][cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]3)[cH:19][cH:20]1)[cH:9][c:10]2[CH2:11][CH2:12][CH2:13][Br:14].[O:52]=[CH:53][N:54]([CH3:55])[CH3:56]>>[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:15]1[cH:16][c:17]([F:36])[c:18]([NH:21][C:22](=[O:23])[NH:24][c:25]3[c:26]([F:35])[cH:27][cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]3)[cH:19][cH:20]1)[cH:9][c:10]2[CH2:11][CH2:12][CH2:13][N:41]1[CH:40]([CH2:39][O:38][CH3:37])[CH2:44][CH2:43][CH2:42]1