2-Bromothiophene → 2-(3-Chlorophenyl)thiophene

반응식

Br[C:2]1[S:3][CH:4]=[CH:5][CH:6]=1.[Cl:7][C:8]1[CH:9]=[C:10](B(O)O)[CH:11]=[CH:12][CH:13]=1>>[Cl:7][C:8]1[CH:13]=[C:12]([C:2]2[S:3][CH:4]=[CH:5][CH:6]=2)[CH:11]=[CH:10][CH:9]=1

참가 물질

반응물 2

HCID 138512-Bromothiophene

HCID 2734323(3-Chlorophenyl)boronic acid

생성물 1

HCID 123624442-(3-Chlorophenyl)thiophene

실험 절차

2-Bromothiophene and 3-chlorophenylboronic acid were treated in a manner similar to Reference Example 26-(2) to give 2-(3-chlorophenyl)thiophene as colorless oil.

출처 및 근거

ORD 기록: ord-9013a09ff47a48008dd3f3a9daf8d549
출처 데이터셋: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08785403B2

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