Glycine tert-butyl ester hydrochloride → Tert-butyl ({[5-(benzyloxy)-6-methyl-2-(piperidin-4-ylmethyl)pyrimidin-4-yl]carbonyl}amino)acetate hydrochloride

반응식

[CH2:1]([O:8][C:9]1[C:10]([C:30](OC(C)(C)C)=[O:31])=[N:11][C:12]([CH2:16][CH:17]2[CH2:22][CH2:21][N:20](C(OC(C)(C)C)=O)[CH2:19][CH2:18]2)=[N:13][C:14]=1[CH3:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC1[C:46]([C:73]([O:75][C:76]([CH3:79])([CH3:78])[CH3:77])=[O:74])=[N:47]C(CC2CCN(C3C=CC(C4C=CC(CO)=CC=4)=CC=3)CC2)=NC=1C)C1C=CC=CC=1.[ClH:80].C(OC(=O)CN)(C)(C)C>>[ClH:80].[C:76]([O:75][C:73](=[O:74])[CH2:46][NH:47][C:30]([C:10]1[C:9]([O:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:14]([CH3:15])[N:13]=[C:12]([CH2:16][CH:17]2[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]2)[N:11]=1)=[O:31])([CH3:79])([CH3:78])[CH3:77]