(4-Bromophenyl)boronic acid → Ethyl (4'-bromobiphenyl-4-yl)acetate

HRID 1626819

반응식

HRID 1626819 반응식
I[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][CH:3]=1.[Br:14][C:15]1[CH:20]=[CH:19][C:18](B(O)O)=[CH:17][CH:16]=1>>[Br:14][C:15]1[CH:20]=[CH:19][C:18]([C:2]2[CH:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][CH:3]=2)=[CH:17][CH:16]=1

참가 물질

3

반응물 2

HCID 79599(4-Bromophenyl)boronic acidHCID 14974990Ethyl (4-iodophenyl)acetate

생성물 1

HCID 70818737Ethyl (4'-bromobiphenyl-4-yl)acetate수율 71%

실험 절차

In accordance with Example 11-(1), but using ethyl 4-iodophenylacetate instead of 4-bromobenzyl bromide, and (4-bromophenyl)boronic acid instead of [3-(hydroxymethyl)phenyl]boronic acid, ethyl (4′-bromobiphenyl-4-yl)acetate (yield 71%) was afforded as a white solid.

출처 및 근거

ORD 기록
ord-0262de864bae46b89b5c44674992fbe0
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08785462B2

연결된 노트

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