4-Bromomethyl-3-chloro-benzenesulfonamide → 3-Chloro-4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)benzenesulfonamide
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]([C:12]2[N:16]([C:17]3[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=3)[C:15](=[S:24])[NH:14][CH:13]=2)([CH3:11])[CH3:10])[CH:5]=[CH:6][C:7]=1[Cl:8].Br[CH2:26][C:27]1[CH:32]=[CH:31][C:30]([S:33]([NH2:36])(=[O:35])=[O:34])=[CH:29][C:28]=1[Cl:37]>>[Cl:37][C:28]1[CH:29]=[C:30]([S:33]([NH2:36])(=[O:34])=[O:35])[CH:31]=[CH:32][C:27]=1[CH2:26][S:24][C:15]1[N:16]([C:17]2[CH:18]=[CH:19][C:20]([F:23])=[CH:21][CH:22]=2)[C:12]([C:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)([CH3:11])[CH3:10])=[CH:13][N:14]=1참가 물질
3
실험 절차
Similarly the title compound was prepared from 5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione and 4-(bromomethyl)-3-chlorobenzenesulfonamide. MS (EI) m/z 584 (MH)+.
출처 및 근거
- ORD 기록
- ord-cf6239d657bb45d9bfb5a21d5d0def1b
- 출처 데이터셋
- uspto-grants-2014_07