HCID 178526599, 화합물 → HCID 178507526, 화합물
반응식
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:14]=[CH:13][NH:12][N:11]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O>CO.[Pd]>[NH:12]1[CH:13]=[CH:14][C:10]([C:6]2[CH:5]=[C:4]([NH2:1])[CH:9]=[CH:8][CH:7]=2)=[N:11]1참가 물질
4
실험 절차
To a solution of 3-(3-nitrophenyl)-1H-pyrazole 12.A (490 mg, 2.59 mmol, available from Oakwood) in methanol (5 mL) was added 10% Pd on carbon by weight (100 mg). The air was evacuated from the reaction flask and was replaced with hydrogen. The resulting slurry was stirred overnight at room temperature. The reaction mixture was filtered, and the mother liquor condensed to afford 3-(1H-pyrazol-3-yl)benzenamine 12.B (397 mg, 96% yield).
후처리
- customThe air was evacuated from the reaction flask
- filtrationThe reaction mixture was filtered
- customthe mother liquor condensed
출처 및 근거
- ORD 기록
- ord-ee33acae7f0a4ba39d4c687744b00a6d
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08785468B2
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