HCID 86632863, 화합물 → HCID 68737549, 화합물

HRID 1628398노트

반응식

HRID 1628398 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-])=O)[C:5]=1[NH:13][CH2:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])([O-])=O>[Pd].O1CCCC1>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([NH2:10])[C:5]=1[NH:13][CH2:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]

참가 물질

4

반응물 1

HCID 86632863HCID 86632863, 화합물

생성물 1

HCID 68737549HCID 68737549, 화합물수율 91.5%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8028Tetrahydrofuran용매

실험 절차

Under hydrogen gas atmosphere, a mixture of ethyl N-(2,6-dinitrophenyl)-beta-alaninate (Reference Example 24; 1.39 g, 4.92 mmol), 10% palladium on carbon (50% wet, 280 mg) and tetrahydrofuran (50 mL) was stirred at room temperature for 6 hr. The reaction mixture was filtered and concentrated in vacuo to give the title compound as an oil (1.00 g, 4.50 mmol, 91%).

후처리

  1. filtrationThe reaction mixture was filtered
  2. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-a381dd530bc34421a714afbb942984fd
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08785460B2

반응 노트

불러오는 중…