Tetrahydrofuran → Ethyl 4-[(2-chloro-ethoxy)-acetyl-amino]-3-fluoro-benzoate
반응식
[Cl:1][CH2:2][CH2:3][O:4]CC(Cl)=O.[NH2:9][C:10]1[CH:20]=[CH:19][C:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:12][C:11]=1[F:21].C1C[O:25][CH2:24][CH2:23]1>>[Cl:1][CH2:2][CH2:3][O:4][N:9]([C:24](=[O:25])[CH3:23])[C:10]1[CH:20]=[CH:19][C:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:12][C:11]=1[F:21]참가 물질
4
실험 절차
Prepared analogously to Example 46a from (2-chloro-ethoxy)-acetylchloride and ethyl 4-amino-3-fluoro-benzoate with TEA in THF.
출처 및 근거
- ORD 기록
- ord-12acf473561f451b894bfb4c54a7a532
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08791103B2
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