5-Chloro-2-(methylthio)aniline → N-[5-chloro-2-(methylthio)phenyl]-5-methylfuran-2-sulfonamide

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH2:8])[CH:7]=1.[CH3:11][C:12]1[O:16][C:15]([S:17](Cl)(=[O:19])=[O:18])=[CH:14][CH:13]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH:8][S:17]([C:15]2[O:16][C:12]([CH3:11])=[CH:13][CH:14]=2)(=[O:19])=[O:18])[CH:7]=1

참가 물질

반응물 2

HCID 27945775-Chloro-2-(methylthio)aniline

HCID 178643615-Methylfuran-2-sulfonyl chloride

생성물 1

HCID 57378991N-[5-chloro-2-(methylthio)phenyl]-5-methylfuran-2-sulfonamide수율 61.2%

실험 절차

Following General Procedure B, the title compound (212 mg, 48%) was prepared from 5-chloro-2-methylsulfanyl-phenylamine (189 mg, 1.09 mmol) and 5-methyl-furan-2-sulfonyl chloride (250 mg, 1.38 mmol).

출처 및 근거

ORD 기록: ord-dcedacd6bd704560a13cb5aed647f488
출처 데이터셋: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08791161B2

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