Carbamic acid, ethyl ester → Ethyl N-tert-butylcarbamate

HRID 1632603노트

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HRID 1632603 반응식
[C:1](=[O:6])([O:3][CH2:4][CH3:5])[NH2:2].[CH2:7]=[C:8]([CH3:10])[CH3:9]>>[C:8]([NH:2][C:1](=[O:6])[O:3][CH2:4][CH3:5])([CH3:10])([CH3:9])[CH3:7]

참가 물질

3

반응물 2

HCID 5641Carbamic acid, ethyl esterHCID 8255Isobutylene

생성물 1

HCID 4189386Ethyl N-tert-butylcarbamate수율 92.4%

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온도
70 °C

실험 절차

A stirred mixture of 89 g of ethyl carbamate, 10 g of ®LEWASORB AC-10 and 70 g of isobutene was heated to 70° C. in a stirred autoclave, and stirring was continued at this temperature for 4 hours. After the reaction was complete, the catalyst was separated off and the reaction mixture was analyzed by gas chromatography. It still contained 4.5 percent by weight of diisobutene, in addition to the end product. Distillation of the crude product gave 134 g (92% of theory) of ethyl N-tert.-butylcarbamate of boiling point 70°-71° C./20 mbar.

후처리

  1. customthe catalyst was separated off
  2. additionIt still contained 4.5 percent by weight of diisobutene, in addition to the end product
  3. distillationDistillation of the crude product

출처 및 근거

ORD 기록
ord-996eea09712e470aa2e9599ac077ac39
출처 데이터셋
uspto-grants-1984_10
특허 번호
US04476316

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