Octanoic Acid → Octanoic anhydride

HRID 1632676

반응식

HRID 1632676 반응식
[C:1]([OH:10])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]>CCCCCCC>[C:1]([O:10][C:1](=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

참가 물질

3

반응물 1

HCID 379Octanoic Acid2회

생성물 1

HCID 69340Octanoic anhydride

시약·촉매·용매 1

HCID 8900Heptane용매2회

반응 조건

온도
200 °C

실험 절차

A glass reactor of 500 ml. capacity and equipped with a mechanical stirrer, temperature control means and a Dean-Stark type condenser was employed. To the reactor were charged 43.5 g. (300 millimols) of octanoic acid and 0.74 g. (3 m mols) of Co(OAc)2.4H2O. About 7 ml. of heptane was also added to the reactor and the Dean-Stark tube was filled with heptane. The reaction mixture was stirred vigorously and heated to 200° C. and nitrogen was bubbled through the reaction mixture at the rate of 50 cc/minute. The reaction was allowed to proceed for 3 hours under these conditions during which about 1 ml of H2O was collected in the Dean-Stark tube. Infrared analysis of the reaction mixture at the end of the 3 hour reaction period showed bands characteristic of the anhydride at 1825 and 1760 cm-1. GLC analysis of the reaction mixture showed that about 12% of the octanoic acid was converted to its anhydride to give 18 m mols of octanoic acid anhydride.

후처리

  1. customcapacity and equipped with a mechanical stirrer
  2. additionTo the reactor were charged 43.5 g
  3. customnitrogen was bubbled through the reaction mixture at the rate of 50 cc/minute
  4. customwas collected in the Dean-Stark tube
  5. customat the end of the 3 hour reaction period

출처 및 근거

ORD 기록
ord-61aecd8df404458592e1729eb51b98fe
출처 데이터셋
uspto-grants-1984_10
특허 번호
US04477382

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