Triethylamine → HCID 20442368, 화합물

HRID 1632740노트

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HRID 1632740 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[S:15][C:14]([S:16]([NH2:19])(=[O:18])=[O:17])=[CH:13][CH:12]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.C(N(CC)CC)C.[CH3:27][O:28][C:29]([CH2:31][CH2:32][C:33](Cl)=[O:34])=[O:30]>CC(C)=O>[CH3:27][O:28][C:29]([CH2:31][CH2:32][C:33]([O:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[S:15][C:14]([S:16](=[O:17])(=[O:18])[NH2:19])=[CH:13][CH:12]=2)(=[O:9])=[O:10])=[CH:4][CH:3]=1)=[O:34])=[O:30]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 73888Butanoic acid, 4-chloro-4-oxo-, methyl esterHCID 127368925-(4-Hydroxyphenyl)sulfonylthiophene-2-sulfonamide

생성물 1

HCID 20442368HCID 20442368, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A solution of 5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide (3.19 g; 0.1 mole) in acetone (60 ml) at -10° was treated with triethylamine (1.11 g; 0.011 mole). Then methoxycarbonylpropionyl chloride (1.66 g; 0.011 mole) was added, dropwise, during 5 minutes at -10°.

출처 및 근거

ORD 기록
ord-ace74607f05a4b5db29b180e6955764d
출처 데이터셋
uspto-grants-1984_10
특허 번호
US04477466

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