Triethylamine → HCID 20442366, 화합물

HRID 1632743노트

반응식

HRID 1632743 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[S:15][C:14]([S:16]([NH2:19])(=[O:18])=[O:17])=[CH:13][CH:12]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.C(N(CC)CC)C.Cl[C:28]([O:30][CH2:31][CH:32]([CH3:34])[CH3:33])=[O:29]>CC(C)=O>[C:28](=[O:29])([O:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[S:15][C:14]([S:16](=[O:17])(=[O:18])[NH2:19])=[CH:13][CH:12]=2)(=[O:9])=[O:10])=[CH:4][CH:3]=1)[O:30][CH2:31][CH:32]([CH3:34])[CH3:33]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 62365Isobutyl chloroformateHCID 127368925-(4-Hydroxyphenyl)sulfonylthiophene-2-sulfonamide

생성물 1

HCID 20442366HCID 20442366, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A solution of 5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide (2.50 g; 0.00783 mole) in acetone (50 ml) at 0° was treated with triethylamine (0.87 g; 0.00861 mole) followed by isobutyl chloroformate (1.17 g; 0.00861 mole) dropwise, during 30 minutes at 0°-2°.

출처 및 근거

ORD 기록
ord-a317db748f864f159b9f04f622f0422b
출처 데이터셋
uspto-grants-1984_10
특허 번호
US04477466

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