Thionyl Chloride → 4-(Chlorocarbonyl)phenyl hexanoate
반응식
[C:1]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13](O)=[O:14])=[CH:11][CH:10]=1)(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].S(Cl)([Cl:20])=O>C1(C)C=CC=CC=1>[C:1]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13]([Cl:20])=[O:14])=[CH:11][CH:10]=1)(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]참가 물질
4
실험 절차
A mixture of 10 g of the resultant 4-hexanoyloxybenzoic acid, 8 g thionyl chloride and 100 ml toluene was stirred and externally heated to be refluxed for three hours. After distilling off the toluene from the mixture, the residue was distilled under reduced pressure to give 8.8 g 4-hexanoyloxybenzoic acid chloride in 82% yield based upon the amount of the 4-hexanoyloxybenzoic acid.
후처리
- temperatureexternally heated
- temperatureto be refluxed for three hours
- distillationAfter distilling off the toluene from the mixture
- distillationthe residue was distilled under reduced pressure
출처 및 근거
- ORD 기록
- ord-ccf83df1dfea44009fa0983dc7eb010d
- 출처 데이터셋
- uspto-grants-1984_10
- 특허 번호
- US04478741
반응 노트
불러오는 중…