Ammonia → HCID 13377346, 화합물

반응식

Cl[C:2]1[N:7]2[C:8]([CH2:11][CH2:12][CH3:13])=[N:9][CH:10]=[C:6]2[CH:5]=[C:4]([Cl:14])[N:3]=1.[NH3:15]>>[NH2:15][C:2]1[N:7]2[C:8]([CH2:11][CH2:12][CH3:13])=[N:9][CH:10]=[C:6]2[CH:5]=[C:4]([Cl:14])[N:3]=1

참가 물질

반응물 2

HCID 222Ammonia

HCID 217939465,7-Dichloro-3-propylimidazo[1,5-c]pyrimidine

생성물 1

HCID 13377346HCID 13377346, 화합물

실험 절차

Using the method of Example 39, 5,7-dichloro-3-(n-propyl)imidazo[1,5-c]pyrimidine (from Example 36) was reacted with ammonia to provide white solid 5-amino-7-chloro-3-(n-propyl)imidazo[1,5-c]pyrimidine, m.p. 160°-161° C. (dec.). Analysis: Calculated for C9H11ClN4 : %C, 51.3; %H, 5.3; %N, 26.6; Found %C, 51.5; %H, 5.2; %N, 26.9.

출처 및 근거

ORD 기록: ord-a5fa0b79244c4152afbc521e40836e15
출처 데이터셋: uspto-grants-1984_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04478835

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