Methyl 4-(2-aminoethyl)benzoate → N-(2-[4-Carbomethoxyphenyl]-1,1-dimethylethyl)-2-hydroxy-2-(4-benzyloxy-3-hydroxymethylphenyl)-ethanamine

참여 물질

역할	이름	HCID	투입량
반응물	Methyl 4-(2-aminoethyl)benzoate	HCID 11183521	—
반응물	4-Benzyloxy-3-hydroxymethylphenylglyoxal	HCID 20134166	—
반응물	Methyl 4-(2-amino-2-methylpropyl)benzoate	HCID 20134200	—
생성물	N-(2-[4-Carbomethoxyphenyl]-1,1-dimethylethyl)-2-hydroxy-2-(4-benzyloxy-3-hydroxymethylphenyl)-ethanamine	HCID 20134220	—

반응 단계

The title compound was prepared by the process of Example 25, replacing phenyl glyoxal by 4-benzyloxy-3-hydroxymethylphenyl glyoxal and 2-(4-carbomethoxyphenyl) ethanamine by 2-(4-carbomethoxyphenyl)-1,1-dimethylethanamine. τ (d6DMSO) 9.06 (6H, s), 7.10-7.60 (5H, m), 6.20 (3H, s), 5.39 (2H, s), 5.00 (1H, m), 4.88 (2H, s), 3.04 (2H, d, J=8 Hz), 2.40-3.00 (10H, m), 2.12 (2H, d, J=8 Hz).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US04478849
출처 데이터셋	uspto-grants-1984_10
ORD ID	ord-2351659d1b70450cbe7f01d8e2c4a901
출처 메모	uspto-grants-1984_10