Aluminum → 1-(4-Carbomethoxyphenyl)propan-2-one oxime
반응식
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[C:12]([N+:14]([O-])=[O:15])[CH3:13])=[CH:7][CH:6]=1)([O:3][CH3:4])=[O:2].[Al]>O1CCCC1>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12](=[N:14][OH:15])[CH3:13])=[CH:7][CH:6]=1)([O:3][CH3:4])=[O:2]참가 물질
4
실험 절차
1-(4-Carbomethoxyphenyl)-2-nitroprop-1-ene (31.0 g) in tetrahydrofuran (900 ml) was stirred with aluminium amalgam, made in the usual way from aluminium (13.5 g) and mercuric chloride (6.9 g). The mixture was cooled in ice and stirring was continued until reaction was complete. The slurry was filtered through celite and the filtrate was evaporated to give a cream solid (17.0 g). τ (CDCl3) 8.27 (3H, s), 6.22 (2H, s), 6.13 (3H, s), 2.63 (2H, d, J=8 Hz), 1.95 (2H, d, J=8 Hz).
후처리
- temperatureThe mixture was cooled in ice
- customwas continued until reaction
- filtrationThe slurry was filtered through celite
- customthe filtrate was evaporated
출처 및 근거
- ORD 기록
- ord-7e8888de7a9945e59cba391a6cda64c6
- 출처 데이터셋
- uspto-grants-1984_10
- 특허 번호
- US04478849
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