Ammonium Chloride → HCID 18679754, 화합물
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[CH3:1][N:2]([CH3:22])[S:3]([N:6]1[CH:10]=[C:9]([C:11](=[O:21])[C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-])=O)[CH:13]=2)[N:8]=[CH:7]1)(=[O:5])=[O:4].[NH4+].[Cl-]>O.C(O)C.[Fe]>[NH2:18][C:14]1[CH:13]=[C:12]([CH:17]=[CH:16][CH:15]=1)[C:11]([C:9]1[N:8]=[CH:7][N:6]([S:3]([N:2]([CH3:22])[CH3:1])(=[O:4])=[O:5])[CH:10]=1)=[O:21]참가 물질
6
실험 절차
To a mixture of Example 55B (3.24 g, 10 mmol) and NH4Cl (540 mg, 10 mmol) in water (15 mL) and ethanol (35 mL) was added iron powder (3.92 g, 70 mmol) and the mixture was refluxed for 1 hour. The mixture was filtered, the solid was washed with THF, and the combined filtrate and washings were removed under vacuum to provide 3 g (˜100%) of the title compound.
후처리
- temperaturethe mixture was refluxed for 1 hour
- filtrationThe mixture was filtered
- washthe solid was washed with THF
- customthe combined filtrate and washings were removed under vacuum
출처 및 근거
- ORD 기록
- ord-bf35df752b1e43ed8b59d1fbd33d4f23
- 출처 데이터셋
- uspto-grants-2003_01
- 특허 번호
- US06503935B1
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