(2S, 3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine → (2S, 3S)-3-(2-Methoxy-5-(1,1,2,2,2-pentafluoroethyl)benzyl)amino-2-phenylpiperidine
반응식
C(OC([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([NH:14][CH2:15][C:16]2[CH:21]=[C:20]([C:22]([F:28])([F:27])[C:23]([F:26])([F:25])[F:24])[CH:19]=[CH:18][C:17]=2[O:29][CH3:30])[C@@H:9]1[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)=O)(C)(C)C.FC(C1C=CC(OC(F)(F)F)=C(C=1)CN[C@H]1CCCN[C@H]1C1C=CC=CC=1)(F)C>>[CH3:30][O:29][C:17]1[CH:18]=[CH:19][C:20]([C:22]([F:28])([F:27])[C:23]([F:24])([F:25])[F:26])=[CH:21][C:16]=1[CH2:15][NH:14][C@H:10]1[CH2:11][CH2:12][CH2:13][NH:8][C@H:9]1[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1참가 물질
3
반응물 2
생성물 1
실험 절차
This compound was prepared from Compound 41 in the same manner of Compound 27.
출처 및 근거
- ORD 기록
- ord-a4d83c26150544c5ab4923e1dd034679
- 출처 데이터셋
- uspto-grants-2003_01
- 특허 번호
- US06506775B1
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