(S,3S)-3-[5-(1,1-Dimethyl-2,2,2-trifluoroethyl)-2-methoxybenzylamino]-2-phenylpiperidine → (2S,3S)-3-[5-(1,1-Dimethyl-2,2,2-trifluoroethyl)-2-methoxybenzylamino]-2-phenylpiperidine dihydrochloride

HRID 1634352노트

반응식

HRID 1634352 반응식
[CH3:1][C:2]([C:8]1[CH:9]=[CH:10][C:11]([O:28][CH3:29])=[C:12]([CH:27]=1)[CH2:13][NH:14][C@H:15]1[CH2:20][CH2:19][CH2:18][NH:17][C@H:16]1[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)([CH3:7])[C:3]([F:6])([F:5])[F:4].[ClH:30].Cl.FC(C1C=CC(OC(F)(F)F)=C(C=1)CN[C@H]1CCCN[C@H]1C1C=CC=CC=1)(F)C>>[ClH:30].[ClH:30].[CH3:7][C:2]([C:8]1[CH:9]=[CH:10][C:11]([O:28][CH3:29])=[C:12]([CH:27]=1)[CH2:13][NH:14][C@H:15]1[CH2:20][CH2:19][CH2:18][NH:17][C@H:16]1[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)([CH3:1])[C:3]([F:4])([F:5])[F:6]

참가 물질

3

실험 절차

This compound was prepared from Compound 73 in the same manner of Compound 28.

출처 및 근거

ORD 기록
ord-1514ab4ab7204a9eb189259a23f0e446
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06506775B1

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