(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochloride → 5-[(1-Chloro-1-(trifluoromethyl)ethyl]-2-methoxybenzylamino]-2-phenylpiperidine dihydrochloride
반응식
[Cl:1][C:2]([N:8]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[O:28][CH3:29])[CH:9]1[CH2:14][NH:13][CH:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:11][CH2:10]1)([C:4]([F:7])([F:6])[F:5])[CH3:3].[ClH:30].Cl.FC(C1C=CC(OC(F)(F)F)=C(C=1)CN[C@H]1CCCN[C@H]1C1C=CC=CC=1)(F)C>>[ClH:1].[ClH:30].[Cl:1][C:2]([N:8]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[O:28][CH3:29])[CH:9]1[CH2:14][NH:13][CH:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:11][CH2:10]1)([C:4]([F:6])([F:5])[F:7])[CH3:3]참가 물질
3
반응물 2
생성물 1
실험 절차
This compound was prepared from Compound 104 in the same manner of Compound 28.
출처 및 근거
- ORD 기록
- ord-3a3c2ddc003e493cbdb06dc10892634c
- 출처 데이터셋
- uspto-grants-2003_01
- 특허 번호
- US06506775B1
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