(1-Propylpiperidin-4-yl)methanamine → 1-(9H-Carbazol-4-yloxy)-3-[(1-propyl-piperidin-4-ylmethyl)-amino]-propan-2-ol
반응식
[O:1]1[CH2:3][C@H:2]1[CH2:4][O:5][C:6]1[C:18]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:11][C:10]=2[CH:9]=[CH:8][CH:7]=1.[NH2:19][CH2:20][CH:21]1[CH2:26][CH2:25][N:24]([CH2:27][CH2:28][CH3:29])[CH2:23][CH2:22]1>>[CH:9]1[C:10]2[NH:11][C:12]3[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=3)[C:18]=2[C:6]([O:5][CH2:4][C@@H:2]([OH:1])[CH2:3][NH:19][CH2:20][CH:21]2[CH2:26][CH2:25][N:24]([CH2:27][CH2:28][CH3:29])[CH2:23][CH2:22]2)=[CH:7][CH:8]=1참가 물질
3
실험 절차
Prepared from 4-[(2S)-oxiranylmethoxy]-9H-carbazole (0.239 g, 1.0 mmol) and 4-aminomethyl-1-propylpiperidine (0.312 g, 2.0 mmol) according to the procedure used for Example 2 to give 0.145 g of the title compound as an off-white solid.
출처 및 근거
- ORD 기록
- ord-a0bc6e7f8224488090e709acb33014f8
- 출처 데이터셋
- uspto-grants-2003_01