Chlorosulfonic acid → HCID 18173760, 화합물

HRID 1634798노트

반응식

HRID 1634798 반응식
[CH2:1]([NH:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[Cl:19][S:20](O)(=[O:22])=[O:21]>>[CH2:1]([NH:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][C:16]([S:20]([Cl:19])(=[O:22])=[O:21])=[CH:15][CH:14]=1)=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

참가 물질

3

반응물 2

HCID 24638Chlorosulfonic acidHCID 3297718HCID 3297718, 화합물

생성물 1

HCID 18173760HCID 18173760, 화합물수율 15.3%

실험 절차

N-octyl-N′-phenylurea (10 g, 215 mmol) was dissolved in chlorosulfonic acid 925 g and stirred for 14 hours at ambient temperature. The reaction was poured into ice and extracted with ethyl acetate. The organic layer was washed with cold, dilute aqueous sodium bicarbonate, then dried (Na2SO4). The solvent was evaporated in vacuo to give the product as a white solid (11.46 g, 33 mmol).

후처리

  1. additionThe reaction was poured into ice
  2. extractionextracted with ethyl acetate
  3. washThe organic layer was washed with cold, dilute aqueous sodium bicarbonate
  4. dry with materialdried (Na2SO4)
  5. customThe solvent was evaporated in vacuo

출처 및 근거

ORD 기록
ord-4a383129635d43a2aba73c5f89fba188
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06506901B2

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