(4-Methoxyphenyl)boronic acid → (4'-Methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

HRID 1635131노트

반응식

HRID 1635131 반응식
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:24]2[CH:25]=[CH:26][C:21]([O:20][CH3:19])=[CH:22][CH:23]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

생성물 1

HCID 69592776(4'-Methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

실험 절차

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 4-methoxyphenylboronic acid according to the general procedure B. Obtained as a yellow solid (637 mg).

출처 및 근거

ORD 기록
ord-de688efa2eb246c3a3ac1492bdc58d5a
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06509328B1

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