2-Bromopyridine → (2-Nitro-4-pyridin-2-yl-phenyl)-carbamic acid tert.-butyl ester

HRID 1635153노트

반응식

HRID 1635153 반응식
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].B1(B2OC(C)(C)C(C)(C)O2)OC(C)(C)C(C)(C)O1.Br[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][N:39]=1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][N:39]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

참가 물질

4

반응물 3

HCID 79732-BromopyridineHCID 2733548Bis(pinacolato)diboraneHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

생성물 1

HCID 69592830(2-Nitro-4-pyridin-2-yl-phenyl)-carbamic acid tert.-butyl ester

실험 절차

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1), bis(pinacolato)diboron and 2-bromopyridine according to the general procedure C. Obtained as a yellow solid (407 mg).

출처 및 근거

ORD 기록
ord-17788a1e1822443c859bc5c240091814
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06509328B1

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