Stannous chloride dihydrate → (2-Amino-4-cyclopropyl-phenyl)-carbamic acid tert-butyl ester

HRID 1635218노트

반응식

HRID 1635218 반응식
[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:16][CH2:15]2)=[CH:10][C:9]=1[N+:17]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:16][CH2:15]2)=[CH:10][C:9]=1[NH2:17])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 2

HCID 61436Stannous chloride dihydrateHCID 69592793(4-Cyclopropyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester

생성물 1

HCID 69592759(2-Amino-4-cyclopropyl-phenyl)-carbamic acid tert-butyl ester

실험 절차

Prepared from (4-cyclopropyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A3) by reduction with SnCl2.2H2O according to the general procedure G (method b). Obtained as a dark solid (1.96 g).

출처 및 근거

ORD 기록
ord-04e42d66e79f469b8e637d09cf1e328e
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06509328B1

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