Oxalyl chloride → HCID 22605448, 화합물
반응식
[CH3:1][C:2]1[CH:6]=[CH:5][N:4]([C:7]2[CH:15]=[CH:14][C:10]([C:11](O)=[O:12])=[CH:9][CH:8]=2)[N:3]=1.C(Cl)(=O)C([Cl:19])=O>ClCCl.CN(C)C=O>[CH3:1][C:2]1[CH:6]=[CH:5][N:4]([C:7]2[CH:15]=[CH:14][C:10]([C:11]([Cl:19])=[O:12])=[CH:9][CH:8]=2)[N:3]=1참가 물질
5
실험 절차
To a suspension of 4-(3-methylpyrazol-1-yl)benzoic acid (1.84 g) in dichloromethane (25 ml) was added oxalyl chloride (1.16 g) and one drop of dimethylformamide. The mixture was stirred at room temperature for 18 hours and the volatile material was removed under reduced pressure. Dichloromethane was added, the solution filtered, and the solvent evaporated under reduced pressure to yield 4-(3-methylpyrazol-1-yl)benzoyl chloride as a yellow oil (1.76 g), which was utilized without further purification.
후처리
- customthe volatile material was removed under reduced pressure
- additionDichloromethane was added
- filtrationthe solution filtered
- customthe solvent evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-ede1adb01eb54cfe948923385d26ae60
- 출처 데이터셋
- uspto-grants-2003_01
- 특허 번호
- US06511974B1
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