참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethoxymethane | HCID 8020 | — |
| 반응물 | (Ethylthio)benzene | HCID 12144 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | 1,2-Dichloroethane | HCID 11 | — |
| 생성물 | 4-(Ethylthio)benzyl chloride | HCID 18673858 | — |
반응 단계
Aluminum chloride (2 g, 15 mmol) was suspended in 8 mL 1,2-dichloroethane and the solution was cooled to 5° C. Dimethoxymethane (0.69 mL, 7.8 mmol) over 10 min. Ethylphenylsulfide (0.88 mL, 6.5 mmol) was added and the mixture was warmed to rt. After 15 h ice water was added and the mixture was extracted with methylene chloride (3×). The combined organic fractions were dried over magnesium sulfate and concentrated. The crude material was used directly in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06511994B2 |
|---|
| 출처 데이터셋 | uspto-grants-2003_01 |
|---|
| ORD ID | ord-28964c644ded4d8ebef150e94210722b |
|---|
| 출처 메모 | uspto-grants-2003_01 |
|---|
