Water → 6-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one

HRID 1636433

반응식

HRID 1636433 반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([CH2:12][CH2:13][CH3:14])=[C:7](Cl)[C:6]=2[CH:16]=1.[CH2:17]([N:19]([CH2:23][CH3:24])[C:20](=[S:22])[S-:21])[CH3:18].[Na+].O>CN(C)C=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([CH2:12][CH2:13][CH3:14])=[C:7]([S:22][C:20](=[S:21])[N:19]([CH2:23][CH3:24])[CH2:17][CH3:18])[C:6]=2[CH:16]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 533728Sodium DiethyldithiocarbamateHCID 193516286-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one

생성물 1

HCID 193516196-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

A solution of 6-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one (0.5 g) in dimethylformamide (2 ml) was treated with sodium diethyldithiocarbamate (0.34 g). The mixture was stirred at room temperature under nitrogen overnight and then poured into water, extracted with diethyl ether and the extract washed with brine, dried and evaporated under reduced pressure to give 6-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one, m.p. 135-7°. (compound 16)

후처리

  1. extractionextracted with diethyl ether
  2. washthe extract washed with brine
  3. customdried
  4. customevaporated under reduced pressure

출처 및 근거

ORD 기록
ord-68208a4527674e13946886f99212d572
출처 데이터셋
uspto-grants-2000_03
특허 번호
US06034121

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