Sodium Carbonate → Sodium 4-(benzoxazol-2-yl)phenylsulphamate

HRID 1636568

반응식

HRID 1636568 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.Cl[S:18]([OH:21])(=[O:20])=[O:19].S(=O)(=O)([O-])N.C(=O)([O-])[O-].[Na+:31].[Na+]>N1C=CC=CC=1C>[O:9]1[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[N:12]=[C:8]1[C:5]1[CH:4]=[CH:3][C:2]([NH:1][S:18](=[O:20])(=[O:19])[O-:21])=[CH:7][CH:6]=1.[Na+:31]

참가 물질

6

반응물 4

HCID 10340Sodium CarbonateHCID 24638Chlorosulfonic acidHCID 88733Benzenamine, 4-(2-benzoxazolyl)-HCID 177700Sulfamate ion

생성물 1

HCID 23717891Sodium 4-(benzoxazol-2-yl)phenylsulphamate수율 96%

시약·촉매·용매 1

HCID 79752-Methylpyridine용매

실험 절차

2(4'-Aminophenyl)benzoxazole was treated with chlorsulphonic acid in 2-picoline and sodium carbonate according to the above-described general procedure for preparation of sulphamate salts. Grey crystals were obtained in 96% yield, m.p. >340° C.

후처리

  1. customGrey crystals were obtained in 96% yield, m.p. >340° C.

출처 및 근거

ORD 기록
ord-f47491470ecc4bfe944459e07bb1f160
출처 데이터셋
uspto-grants-2000_03
특허 번호
US06034246

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