Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → 5,10-Dimethyl-5,10-dihydrobenzo(a)phenazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 반응물 | Benzo(A)Phenazine | HCID 136045 | — |
| 반응물 | Potassium alloy, nonbase, K,Na | HCID 16211683 | — |
| 생성물 | 5,10-Dimethyl-5,10-dihydrobenzo(a)phenazine | HCID 22055362 | — |
반응 단계
This phenazine was reduced with a 3:1 potassium/sodium metal alloy in dimethoxyethane, to the brick red alkali metal adduct. Alkylation occurred over 1 hour with addition of iodomethane. Residual K/Na alloy was quenched with addition of ethanol. The product was isolated with column chromatography and was recrystallized from ethylacetate/hexane. 2.0 grams of product was isolated for a 38% overall yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06037471 |
| 출처 데이터셋 | uspto-grants-2000_03 |
| ORD ID | ord-92763d2a8cbd489e9ba6de65231fc4ed |
| 출처 메모 | uspto-grants-2000_03 |