2-Bromoethyl methyl ether → Methyl 3-[2-methoxy-4-(2-methoxyethoxy)phenyl]-5-methylhexanoate

반응식

[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH2:14][CH:15]([CH3:17])[CH3:16])[CH2:9][C:10]([O:12][CH3:13])=[O:11])=[C:4]([O:18][CH3:19])[CH:3]=1.[CH3:20][O:21][CH2:22][CH2:23]Br>>[CH3:19][O:18][C:4]1[CH:3]=[C:2]([O:1][CH2:23][CH2:22][O:21][CH3:20])[CH:7]=[CH:6][C:5]=1[CH:8]([CH2:14][CH:15]([CH3:17])[CH3:16])[CH2:9][C:10]([O:12][CH3:13])=[O:11]

참가 물질

반응물 2

HCID 809722-Bromoethyl methyl ether

HCID 19348568Methyl 3-(4-hydroxy-2-methoxyphenyl)-5-methylhexanoate

생성물 1

HCID 19348474Methyl 3-[2-methoxy-4-(2-methoxyethoxy)phenyl]-5-methylhexanoate

실험 절차

Following a similar procedure to that described in Preparation 45A(i), but using methyl 3-(4-hydroxy-2-methoxyphenyl)-5-methylhexanoate (prepared as described in Preparation 58B) and 2-methoxyethyl bromide, the title compound was obtained as an oily substance.

후처리

customthat described in Preparation 45A(i)

출처 및 근거

ORD 기록: ord-e08ec836b8e64b0ab48f74c6c35ffd4c
출처 데이터셋: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06040339

반응 노트

불러오는 중…